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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHC1
All Species:
22.73
Human Site:
S261
Identified Species:
55.56
UniProt:
P29353
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29353
NP_001123512.1
583
62822
S261
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Chimpanzee
Pan troglodytes
XP_513843
473
51606
A226
M
A
G
F
D
G
S
A
W
D
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001112447
583
62797
S261
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Dog
Lupus familis
XP_547561
576
62206
S254
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P98083
579
62589
S261
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Rat
Rattus norvegicus
Q5M824
469
51485
F222
P
H
D
R
M
A
G
F
D
G
S
A
W
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512200
548
59956
G255
Q
S
V
I
S
T
V
G
Q
A
F
E
L
R
F
Chicken
Gallus gallus
XP_428819
632
69780
S276
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Frog
Xenopus laevis
Q8AY68
465
51711
A218
V
T
P
H
D
R
M
A
G
F
D
G
S
A
W
Zebra Danio
Brachydanio rerio
XP_001921625
593
63809
S294
N
H
H
M
Q
S
I
S
F
A
S
G
G
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99.1
94.3
N.A.
94.5
76.8
N.A.
48.8
46.8
64.6
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.9
99.4
96.2
N.A.
96.7
78.3
N.A.
62.6
62.5
69.9
76.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
20
N.A.
6.6
100
6.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
26.6
N.A.
26.6
100
20
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
20
0
70
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
20
0
0
0
10
10
10
0
0
70
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
20
10
10
20
% E
% Phe:
0
0
0
10
0
0
0
10
60
10
10
0
0
0
10
% F
% Gly:
0
0
10
0
0
10
10
10
10
10
0
70
60
0
0
% G
% His:
0
70
60
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
60
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
10
0
0
60
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
60
% P
% Gln:
10
0
0
0
60
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
10
60
10
60
0
0
70
0
10
0
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _